COMPLEXES OF USHER PROTEINS PREASSEMBLE AT THE ENDOPLASMIC RETICULUM AND ARE REQUIRED FOR TRAFFICKING AND ER HOMEOSTASIS

Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis

Usher syndrome (USH), the leading cause of hereditary combined hearing and vision loss, is characterized by sensorineural deafness and progressive retinal degeneration.Mutations in several different genes produce USH, but the proximal cause of sensory cell death remains mysterious.We adapted a proximity ligation assay to analyze associations among

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Cutaneous Erythema at Scar Site of Modified Radical Mastectomy: An Unexpected Manifestation of Recurrent Carcinoma

A 44-year-old woman presented with marked erythema over right mastectomy scar, while on Herceptin therapy.She B12 FOLATE had neoadjuvant chemotherapy, modified radical mastectomy, and radiotherapy less than one year earlier for the treatment of invasive ductal carcinoma.On physical examination, no palpable masses were detected in the erythematous s

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Red Ring Nematode, Bursaphelenchus cocophilus (Cobb) Baujard (Nematoda: Secernentea: Tylenchida: Aphelenchina: Aphelenchoidea: Bursaphelechina) formerly Rhadinaphelenchus cocophilus

Bursaphelenchus cocophilus causes red ring disease of palms.Symptoms of red ring disease were first described on Trinidad coconut palms in 1905.Red ring disease can appear in several species of tropical palms, including date, Canary Island date and Cuban royal, but is most common in oil and coconut palms.The red ring nematode parasitizes the palm w

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